CD4 3D structures

3D structures of CD43D structures of CD4

Updated on 20-January-2025

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• CD4 domains; D1-D2 26-202; D3-D4 210-386; extracellular 26-388; tail 403-458; transmembrane 397-403
  • 3cd4, 1cdh, 1cdi, 1cdj – hCD4 D1-D2 domains - human
    
  • 1cdu, 1cdy – hCD4 D1-D2 domains (mutant)
    
  • 1wio, 1wip, 1wiq – hCD4 D1-D4 domains
    
  • 2klu – hCD4 transmembrane and tail domains - NMR
    
  • 1cid – rCD4 D3-D4 domains - rat
    
• CD4 binary complex
  • 3b71 – hCD4 tail + focal adhesion kinase 1
    
  • 3o2d, 4q9i – hCD4 D1-D2 domains + antibody
    
  • 8w90 – hCD4 D1-D2 domains + nanobody
    
  • 5cay, 6l1y – hCD4 D1-D2 domains + gp120
    
  • 1q68 – hCD4 tail + Lck peptide - NMR
    
• CD4 higher complexes
  • 1gc1, 1g9m, 1g9n, 1rzj, 1rzk, 2b4c, 2nxy, 2nxz, 2ny0, 2ny1, 2ny2, 2ny3, 2ny4, 2ny5, 2ny6, 3jwd, 3jwo, 4jm2, 4rqs, 4r2g, 4p9h, 4h8w, 5a8h, 5a7x, 6tyb – hCD4 D1-D2 domains + antibody + gp120
    
  • 3j70, 5u1f, 6u0l, 6u0n – hCD4 D1-D2 domains + antibody + gp120 + gp41 – Cryo EM
    
  • 5thr – hCD4 D1-D2 domains + antibody + gp120 + gp41 + 8ANC195 – Cryo EM
    
  • 2qad, 3lqa – hCD4 D1-D2 domains + antibody + gp160
    
  • 7t0o, 7t0r – hCD4 D1-D4 domains + antibody + adnectin – Cryo EM
    
  • 5vn3, 6cm3, 6edu – hCD4 D1-D2 domains + antibody + gp160 – Cryo EM
    
  • 1jl4 – hCD4 D1-D2 domains + class II MHC + ovotransferin peptide
    
  • 3s4s – hCD4 D1-D2 domains + class II MHC + haemaglutinin peptide
    
  • 3s5l – hCD4 D1-D2 domains + class II MHC + HA peptide
    
  • 3t0e – hCD4 D1-D2 domains + class II MHC + TCR
    
  • 6meo, 6met – hCD4 D1-D3 domains + CCR5 + gp120 – Cryo EM
    
  • 8fyi, 8fyj – hCD4 extracellular domain + HIV-gp41 + gp160 – Cryo EM
    
  • 8z7n – hCD4 extracellular domain + HIV-gp160 – Cryo EM
    
  • 6x5c, 8d5c – hCD4 D1-D2 domain + HIV-gp41 + gp160 + inhibitor – Cryo EM
    
  • 6x5b – hCD4 D1-D2 domain + HIV-gp41 + gp120 + antibody + inhibitor – Cryo EM
    
  • 7txd – hCD4 D1-D2 domain + HIV-gp41 + gp120 + darpin – Cryo EM