Basic Pancreatic Trypsin Inhibitor

Function Basic Pancreatic Trypsin Inhibitor (BPTI) is a small protein which inhibits trypsin and related proteases. For other trypsin inhibitors see Trypsin inhibitor. Relevance BPTI is used as drug called Aprotinin used to reduce bleeding during surgery. Structural highlights extends into the active site of trypsin and inhibits its proteolytic function. 3D Structures of BPTI BPTI 3D structures

spinqualitylabelsall models Bovine BPTI (in salmon) complex with trypsin (magenta), sulfate and Ca+2 ion (green) (PDB code 3tgi) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image