BRCA 3D structures

3D structures of BRCA3D structures of BRCA

Updated on 28-June-2020

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• BRCA1; Domains – Ring 1-110; SUMO-interacting motif 37-49; BRCT 1646-1859; BRCT-C 1755-1863
  • 4ofb, 4y18, 4y2g, 4u4a, 4jlu, 4ifi, 4igk, 3k0h, 3k0k, 3coj, 1y98, 1t15, 1t29, 1t2v - hBRCA1 BRCT1 domain + peptide inhibitor - human
    
  • 3pxa, 3pxb, 3pxc, 3pxd, 3pxe, 3k15, 3k16 - hBRCA1 BRCT1 domain (mutant) + peptide inhibitor
    
  • 1jnx - hBRCA1 BRCT domain
    
  • 2ing, 1t2u, 1n5o - hBRCA1 BRCT1 domain (mutant)
    
  • 1oqa - hBRCA1 BRCT-C domain - NMR
    
  • 2n9e - hBRCA1 SUMO-interacting motif + small ubiquitin-related modifier - NMR
    
  • 4mkf, 4mkg - hBRCA1 SUMO-interacting motif - NMR
    
  • 1jm7 - hBRCA1 Ring domain + BARD1 ring domain - NMR
    
  • 6r8f - hBRCA1-A + SHMT2 – Cryo EM
    
  • 1l0b - BRCA1 BRCT domain - rat
    
  • 6gvw - mBRCA1-A - mouse
    
  • 6h3c - mBRCA1-A + SHMT2 – Cryo EM
    
• BRCA2
  • 1iyj, 1miu – hBRCA2 residues 2335-3151 + DSS1
    
  • 1mje – hBRCA2 residues 2335-3151 + DSS1 + ssDNA
    
  • 1n0w – hBRCA2 BRC repeat 4 residues 1517-1551 + RAD51 + linker