Adenylyl cyclase 3D structures

3D Structures of Adenylyl cyclase3D Structures of Adenylyl cyclase

Updated on 12-September-2024

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• ADCY
  • 8sl4 – hADCY 5 - human - Cryo EM
    
  • 8sl3 – hADCY 5 + G protein + geranyl - Cryo EM
    
  • 8buz, 8bv5 – bADCY 8 + G protein + forskolin + GSP – bovine - Cryo EM
    
  • 7pd4 – bADCY 9 - bovine - Cryo EM
    
  • 1ab8 – ADCY C2 domain - rat
    
  • 8h92 – ADCY - jujube
    
  • 7yz9, 7yzi, 7yzk – MtADCY + nanobody + GDP derivative - Mycobacterium tuberculosis - Cryo EM
    
  • 4p2m, 4p2x – MtADCY residues 212-443
  • 1y10, 1y11 – MtADCY residues 1-397
  • 4p2f – MtADCY (mutant)
    
  • 4wp3 – MaADCY – Mycobacterium avium
    
  • 2fjt – ADCY 4 – Yersinia pestis
    
  • 1ykd – ADCY – Anabaena
    
• Photoactivated adenylyl cyclase
  • 5m27, 5m2a, 5mbb, 5mbc, 5mbd, 5mbe – BePAC subunit b + FMN – Beggiatoa
    
  • 5mbg, 5mbh, 5mbj, 5mbk, 5nby – BePAC subunit b (mutant) + FMN
    
  • 5x4t, 5x4u, 5x4v – PAC + FMN – Oscillatoria acuminata
    
• ADCY catalytic domain residues 1-469
  • 4clf, 4cly, 4cm2, 4oyw, 8il7 – hADCY 10 – human
    
  • 4clk, 4clw, 4cm0, 4usw – hADCY 10 + ATP derivative
    
  • 4clp, 4oyx, 4usu – hADCY 10 + AMP derivative
    
  • 4cll, 4clz, 4oya, 4oyb, 4oyi, 4oym, 4oyo, 4oyp, 4oyz, 4oz2, 4oz3 – hADCY 10 + bicarbonate
    
  • 4cls, 4clu, 4ust, 4usv – hADCY 10 + pyrophosphate
    
  • 4clt – hADCY 10 + pyrophosphate + AMP derivative
    
  • 5d0r, 5iv4, 7ovd, 8b75, 8cnh, 8co7, 8coj, 8cot – hADCY 10 + inhibitor
    
  • 5iv3 – hADCY 10 + inhibitor + ATP derivative
    
  • 6r3q, 6r4o, 6r4p – bADCY 9 + guanine nucleotide-binding protein - Cryo EM
    
  • 3maa – dADCY 5 (mutant)+ADCY 2 C2a+guanine nucleotide binding protein G – dog
    
  • 3g82 - dADCY 5 (mutant)+ADCY 2 C1a+guanine nucleotide binding protein G
    
  • 3c14, 3c15 - dADCY 5 C1a (mutant)+ADCY 2 C2a+guanine nucleotide binding protein G+PPi+ions
    
  • 3c16 - dADCY 5 C1a (mutant)+ADCY 2 C2a+guanine nucleotide binding protein G+ATP+Ca
    
  • 2gvd, 2gvz - dADCY 5 C1a +ADCY 2 C2a+guanine nucleotide binding protein G+ATP+Mn
    
  • 1tl7, 1u0h - dADCY 5 C1a +ADCY 2 C2a+guanine nucleotide binding protein G+GTP+Mn
    
  • 1cs4 - dADCY 5 C1a +ADCY 2 C2a+guanine nucleotide binding protein G+AMP+Mg+PPI+GDP
    
  • 1cul - dADCY 5 C1a +ADCY 2 C2a+guanine nucleotide binding protein G+GDP+Mg+triphosphate
    
  • 1cjk - dADCY 5 C1a +ADCY 2 C2a+guanine nucleotide binding protein G+ATP+Mn+Mg
    
  • 1cjt - dADCY 5 C1a +ADCY 2 C2a+guanine nucleotide binding protein G+GDP+Mn+Mg+ATP
    
  • 1cju - dADCY 5 C1a +ADCY 2 C2a+guanine nucleotide binding protein G+GDP+Mg+ATP
    
  • 1cjv - dADCY 5 C1a +ADCY 2 C2a+guanine nucleotide binding protein G+GDP+Mg+Zn+ATP
    
  • 1azs - dADCY 5 C1a +ADCY 2 C2a+guanine nucleotide binding protein G+GDP+Mg
    
  • 3r5g - ADCY – Pseudomonas aeruginosa
    
  • 1yk9, 1ybt, 1ybu – MtADCY
    
• ADCY complex
  • 6r3q, 6r4o, 6r4p, 7pdf – bADCY 9 + guanine nucleotide-binding protein - Cryo EM
    
  • 7pde – bADCY 9 + guanine nucleotide-binding protein + GDP derivative - Cryo EM
    
  • 7pd8, 7pdd, 7pdg, 7pdh – bADCY 9 + DARPin C4 - Cryo EM
    
  • 4wp8, 4wp9 – MaADCY + ATP derivative
    
  • 4wpa – MaADCY residues 53-216 + pyrophosphate
    
  • 1fx2, 1fx4 - ADCY 888-1123 – Trypanosoma brucei
    
  • 2bw7 - SpADCY catalytic domain+catechol estrogen – Spirulina platensis
    
  • 1wc0 – SpADCY catalytic domain+methylene ATP
    
  • 1wc1, 1wc3, 1wc4, 1wc5, 1wc6 - SpADCY catalytic domain+ATP derivatives
    
• Adenylate/nucleotidyl cyclase toxin (For anthrax edema factor see Anthrax edema factor 3D structures)
  • 2col, 1zot, 1yru, 1yrt - CyaA adenylate cyclase toxin – Bordetella pertussis
    
  • 5xnw – ExoY nucleotidyl cyclase toxin – Pseudomonas aeruginosa
    
  • 6uzb, 6uzd, 6uze – BaADCY + antigen – Cryo EM
    
• ADCY-associated protein
  • 1k8f - hCAP C-terminal
    
  • 6fm2 - mCAP residues 317-474 + actin + ADP – mouse
    
  • 6fm2 - mCAP residues 317-474 + actin + ADP – mouse
    
  • 6rsq - mCAP HFD domain residues 41-216
    
  • 6rsw - mCAP HFD domain (mutnt) + actin + twinfilin
    
  • 1k4z - yCAP C-terminal – yeast
    
  • 1kq5 - yCAP C-terminal (mutant)
    
  • 1s0p, 1tjf - CAP N-terminal – Dictyostelium discoideum