Aspartate-semialdehyde dehydrogenase

Function Aspartate-semialdehyde dehydrogenase (ASADH) is an enzyme which is part of the biosynthesis of amino acids in bacteria, plants and fungi. It catalyzes the conversion of L-aspartate 4-semialdehyde (ASA) + phosphate + NADP to L-4-aspartyl phosphate + NADPH + H+. Structural highlights ASADH contains 2 domains. The N terminal domain contains the and the . The active site contains a (C134 in Vibrio Cholerae) which binds to inhibitors. The C terminal contains the homodimer intersubunit contacts. 3D Structures of Aspartate-semialdehyde dehydrogenase Aspartate-semialdehyde dehydrogenase 3D structures

spinqualitylabelsall models Aspartate-semialdehyde dehydrogenase complex with NADP and substrate analog (PDB code 1mb4) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image