9jr2

Cryo-EM structure of PTH-PTH1R-Gq (upright state)Cryo-EM structure of PTH-PTH1R-Gq (upright state)

Structural highlights

9jr2 is a 6 chain structure with sequence from Bos taurus, Homo sapiens, Mus musculus and Rattus rattus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 2.8Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GBB1_RAT Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

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OCA