Cryo-EM structure of Thogoto virus polymerase in transcription reception conformationCryo-EM structure of Thogoto virus polymerase in transcription reception conformation

Structural highlights

8z98 is a 4 chain structure with sequence from Thogoto virus (isolate SiAr 126). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.52Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PA_THOGV Initiates transcription by a unique cap-stealing mechanism that involves the cleavage of only the m(7)GpppAm structure from cellular hnRNAs.

8z98, resolution 2.52Å

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OCA