8tmw

HTLV-1 capsid protein N-terminal domain triclinic crystal form with sulphate ionHTLV-1 capsid protein N-terminal domain triclinic crystal form with sulphate ion

Structural highlights

8tmw is a 1 chain structure with sequence from HTLV-1 subtype C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.71Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

U3RC00_9DELA Binds strongly to viral nucleic acids and promote their aggregation. Also destabilizes the nucleic acids duplexes via highly structured zinc-binding motifs.[ARBA:ARBA00002374] Forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.[ARBA:ARBA00037500] Matrix protein.[ARBA:ARBA00003230] The matrix domain targets Gag, Gag-Pro and Gag-Pro-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus.[ARBA:ARBA00037194]

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OCA