Structural highlights
Function
NGT_ACTP2 Inverting glycosyltransferase that catalyzes the transfer of one glucose moiety from UDP-glucose to an asparagine residue in peptides and proteins containing the NX(S/T) motif, resulting in their modification with a beta-linked 1,N-glucose. Likely acts as a key component of a general protein glycosylation system (Probable).[1]
References
- ↑ Schwarz F, Fan YY, Schubert M, Aebi M. Cytoplasmic N-glycosyltransferase of Actinobacillus pleuropneumoniae is an inverting enzyme and recognizes the NX(S/T) consensus sequence. J Biol Chem. 2011 Oct 7;286(40):35267-74. PMID:21852240 doi:10.1074/jbc.M111.277160