8iom

Crystal structure of the carboxy-terminal channel-forming domain of Colicin IbCrystal structure of the carboxy-terminal channel-forming domain of Colicin Ib

Structural highlights

8iom is a 1 chain structure with sequence from Shigella flexneri. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A0A200P0K8_SHIFL Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.[ARBA:ARBA00003197] This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.[ARBA:ARBA00002178]

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