Proteopedia

8io3

Cryo-EM structure of human HCN3 channel with cilobradineCryo-EM structure of human HCN3 channel with cilobradine

Structural highlights

8io3 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.02Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HCN3_HUMAN Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions.[1]

References

  1. ↑ Stieber J, Stöckl G, Herrmann S, Hassfurth B, Hofmann F. Functional expression of the human HCN3 channel. J Biol Chem. 2005 Oct 14;280(41):34635-43. PMID:16043489 doi:10.1074/jbc.M502508200

8io3, resolution 3.02Å

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OCA
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