8heq

Solution structure of the periplasmic domain of the anti-sigma factor RsgI2 from Clostridium thermocellumSolution structure of the periplasmic domain of the anti-sigma factor RsgI2 from Clostridium thermocellum

Structural highlights

8heq is a 2 chain structure with sequence from Acetivibrio thermocellus DSM 1313. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RSGI2_ACET2 Anti-sigma factor for SigI2. Negatively regulates SigI2 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI2 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI2.[UniProtKB:A3DBH1]

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