Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex harboring a terminal mismatchCryo-EM structure of E. coli RNA polymerase backtracked elongation complex harboring a terminal mismatch

Structural highlights

8fix is a 8 chain structure with sequence from Escherichia coli K-12 and Escherichia phage Lambda. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RPOA_ECOLI DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]

See Also

8fix, resolution 3.90Å

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OCA