N-terminal WD40 domain of beta'-COPI subunit with two chains in the asymmetric unitN-terminal WD40 domain of beta'-COPI subunit with two chains in the asymmetric unit

Structural highlights

8ewx is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.24Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

G2WDW6_YEASK The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.[PIRNR:PIRNR005567]

8ewx, resolution 1.24Å

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OCA