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Crystal structure of human Sar1a in complex with GDPCrystal structure of human Sar1a in complex with GDP
Structural highlights
FunctionSAR1A_HUMAN Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).[1] References
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