8d9y

Crystal structure of Taipan alpha-neurotoxin in complex with Centi-LNX-D09 antibodyCrystal structure of Taipan alpha-neurotoxin in complex with Centi-LNX-D09 antibody

Structural highlights

8d9y is a 12 chain structure with sequence from Homo sapiens and Oxyuranus scutellatus scutellatus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.2Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

3L21_OXYSC Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.[UniProtKB:P60615]

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OCA