8aey

3 A CRYO-EM STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FERRITIN FROM TIMEPIX3 detector3 A CRYO-EM STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS FERRITIN FROM TIMEPIX3 detector

Structural highlights

8aey is a 24 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 3.05Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BFRB_MYCTU Iron-storage protein that displays ferroxidase activity, catalyzing the oxidation of Fe(2+) ions into Fe(3+) ions, that can then be deposited as a ferric-oxide mineral core within the central cavity of the protein complex.^[1]

References

↑ Khare G, Gupta V, Nangpal P, Gupta RK, Sauter NK, Tyagi AK. Ferritin Structure from Mycobacterium tuberculosis: Comparative Study with Homologues Identifies Extended C-Terminus Involved in Ferroxidase Activity. PLoS One. 2011 Apr 8;6(4):e18570. PMID:21494619 doi:10.1371/journal.pone.0018570

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OCA

[1] Khare G, Gupta V, Nangpal P, Gupta RK, Sauter NK, Tyagi AK. Ferritin Structure from Mycobacterium tuberculosis: Comparative Study with Homologues Identifies Extended C-Terminus Involved in Ferroxidase Activity. PLoS One. 2011 Apr 8;6(4):e18570. PMID:21494619 doi:10.1371/journal.pone.0018570

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