7y1j

Structure of SUR2A in complex with Mg-ATP and repaglinide in the inward-facing conformation.Structure of SUR2A in complex with Mg-ATP and repaglinide in the inward-facing conformation.

Structural highlights

7y1j is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 3Å
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ABCC9_RAT Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.

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OCA