7xlf

Crystal structure of CH3-THF complex of methylenetetrahydrofolate reductase from Sphingobium sp. SYK-6Crystal structure of CH3-THF complex of methylenetetrahydrofolate reductase from Sphingobium sp. SYK-6

Structural highlights 7xlf is a 2 chain structure with sequence from Sphingobium sp. SYK-6. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.85Å Ligands: , , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function METF_SPHSK Catalyzes the NADH-dependent reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate. Is required to provide the methyl group necessary for methionine synthetase to convert homocysteine to methionine; the methyl group is given by 5-methyltetrahydrofolate (By similarity). Is required for Sphingobium SYK-6 to grow on vanillate or syringate as the sole source of carbon (Ref.3).[UniProtKB:P0AEZ1][REFERENCE:3] See Also Methylenetetrahydrofolate reductase 3D structures

spinqualitylabelsall models 7xlf, resolution 1.85Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image