7lcb
C1B domain of Protein kinase C in complex with prostratin and phosphatidylcholineC1B domain of Protein kinase C in complex with prostratin and phosphatidylcholine
Structural highlights
FunctionA0A140UHX0_RAT Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.[PIRNR:PIRNR000551] See Also |
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