Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gq complexCryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gq complex

Structural highlights

7ezm is a 6 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GBG2_HUMAN Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).

See Also

7ezm, resolution 2.90Å

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