6v1x

Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: TetramerCryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Tetramer

Structural highlights

6v1x is a 4 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 3.5Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KAT1_ARATH Highly selective inward-rectifying potassium channel. This voltage-gated channel could mediate long-term potassium influx into guard cells leading to stomatal opening. Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by hyperpolarization. The channel activity is enhanced upon external acidification. Also permeable to ammonium ions. Blocked by tetraethylammonium and barium ions.^[1]

References

↑ Schachtman DP, Schroeder JI, Lucas WJ, Anderson JA, Gaber RF. Expression of an inward-rectifying potassium channel by the Arabidopsis KAT1 cDNA. Science. 1992 Dec 4;258(5088):1654-8. PMID:8966547

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OCA

[1] Schachtman DP, Schroeder JI, Lucas WJ, Anderson JA, Gaber RF. Expression of an inward-rectifying potassium channel by the Arabidopsis KAT1 cDNA. Science. 1992 Dec 4;258(5088):1654-8. PMID:8966547

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