6urg

Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complexCryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex

6urg, resolution 3.00Å Show:Asymmetric Unit Biological Assembly Structural highlights 6urg is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3Å Ligands: Experimental data: Check Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CPSF1_HUMAN Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. See Also WD-repeat protein 3D structures