6uos

MicroED structure of OsPYL/RCAR5 (24-29) at 6 e-/A^2MicroED structure of OsPYL/RCAR5 (24-29) at 6 e-/A^2

Structural highlights

6uos is a 1 chain structure with sequence from Oryza sativa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron crystallography, Resolution 0.9Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PYL5_ORYSJ Intracellular abscisic acid (ABA) receptor that functions as a positive regulator of ABA signaling pathway (PubMed:22071266, PubMed:24474809). Together with ABI5, PP2C30 and SAPK2, is part of an ABA signaling unit that modulates seed germination and early seedling growth (PubMed:22071266). Acts as positive regulator of abiotic stress-responsive gene expression (PubMed:24474809). Inhibits the protein phosphatases PP2C06 and PP2C09 when activated by ABA (PubMed:24743650).^[1] ^[2] ^[3]

References

↑ Kim H, Hwang H, Hong JW, Lee YN, Ahn IP, Yoon IS, Yoo SD, Lee S, Lee SC, Kim BG. A rice orthologue of the ABA receptor, OsPYL/RCAR5, is a positive regulator of the ABA signal transduction pathway in seed germination and early seedling growth. J Exp Bot. 2012 Jan;63(2):1013-24. doi: 10.1093/jxb/err338. Epub 2011 Nov 9. PMID:22071266 doi:http://dx.doi.org/10.1093/jxb/err338
↑ Kim H, Lee K, Hwang H, Bhatnagar N, Kim DY, Yoon IS, Byun MO, Kim ST, Jung KH, Kim BG. Overexpression of PYL5 in rice enhances drought tolerance, inhibits growth, and modulates gene expression. J Exp Bot. 2014 Feb;65(2):453-64. doi: 10.1093/jxb/ert397. PMID:24474809 doi:http://dx.doi.org/10.1093/jxb/ert397
↑ He Y, Hao Q, Li W, Yan C, Yan N, Yin P. Identification and characterization of ABA receptors in Oryza sativa. PLoS One. 2014 Apr 17;9(4):e95246. doi: 10.1371/journal.pone.0095246. eCollection, 2014. PMID:24743650 doi:http://dx.doi.org/10.1371/journal.pone.0095246

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OCA

[1] Kim H, Hwang H, Hong JW, Lee YN, Ahn IP, Yoon IS, Yoo SD, Lee S, Lee SC, Kim BG. A rice orthologue of the ABA receptor, OsPYL/RCAR5, is a positive regulator of the ABA signal transduction pathway in seed germination and early seedling growth. J Exp Bot. 2012 Jan;63(2):1013-24. doi: 10.1093/jxb/err338. Epub 2011 Nov 9. PMID:22071266 doi:http://dx.doi.org/10.1093/jxb/err338

[2] Kim H, Lee K, Hwang H, Bhatnagar N, Kim DY, Yoon IS, Byun MO, Kim ST, Jung KH, Kim BG. Overexpression of PYL5 in rice enhances drought tolerance, inhibits growth, and modulates gene expression. J Exp Bot. 2014 Feb;65(2):453-64. doi: 10.1093/jxb/ert397. PMID:24474809 doi:http://dx.doi.org/10.1093/jxb/ert397

[3] He Y, Hao Q, Li W, Yan C, Yan N, Yin P. Identification and characterization of ABA receptors in Oryza sativa. PLoS One. 2014 Apr 17;9(4):e95246. doi: 10.1371/journal.pone.0095246. eCollection, 2014. PMID:24743650 doi:http://dx.doi.org/10.1371/journal.pone.0095246

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