Structure of Human Cytochrome P450 1A1 with Duocarmycin Prodrug (S) ICT-2700Structure of Human Cytochrome P450 1A1 with Duocarmycin Prodrug (S) ICT-2700

Structural highlights

6udl is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.85Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CP1A1_HUMAN Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

6udl, resolution 2.85Å

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OCA