6o6e

Crystal structure of PltF trapped with PltL using a proline adenosine vinylsulfonamide inhibitorCrystal structure of PltF trapped with PltL using a proline adenosine vinylsulfonamide inhibitor

Structural highlights 6o6e is a 2 chain structure with sequence from Pseudomonas protegens Pf-5. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.14Å Ligands: , , , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PLTF_PSEF5 Involved in the biosynthesis of pyoluteorin. Catalyzes the conversion of L-proline to L-prolyl-AMP and the transfer of the L-prolyl group to acyl carrier protein PltL. Publication Abstract from PubMed Using a covalent chemical probe and X-ray crystallography coupled to nuclear magnetic resonance data, we elucidated the dynamic molecular basis of protein recognition between the carrier protein and adenylation domain in pyoluteorin biosynthesis. These findings reveal a unique binding mode, which contrasts previously solved carrier protein and partner protein interfaces. Dynamic visualization of type II peptidyl carrier protein recognition in pyoluteorin biosynthesis.,Corpuz JC, Podust LM, Davis TD, Jaremko MJ, Burkart MD RSC chem biol. 2020 Apr 1;1(1):8-12. doi: 10.1039/c9cb00015a. Epub 2020 Mar 24. PMID:33305272 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

spinqualitylabelsall models 6o6e, resolution 2.14Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image