6nnc

Structure of Dihydrofolate reductase from Mycobacterium tuberculosis in complex with NADPH and pemetrexedStructure of Dihydrofolate reductase from Mycobacterium tuberculosis in complex with NADPH and pemetrexed

Structural highlights 6nnc is a 2 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.8Å Ligands: , , , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DYR_MYCTU Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. See Also Dihydrofolate reductase 3D structures

spinqualitylabelsall models 6nnc, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image