6igs
Crystal structure of HPRT from F. tularensis with ZincCrystal structure of HPRT from F. tularensis with Zinc
Structural highlights
FunctionQ5NI77_FRATT Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.[ARBA:ARBA00003637] See Also |
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