Crystal structure of HPRT from F. tularensis with ZincCrystal structure of HPRT from F. tularensis with Zinc

Structural highlights

6igs is a 4 chain structure with sequence from Francisella tularensis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.16Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q5NI77_FRATT Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.[ARBA:ARBA00003637]

See Also

6igs, resolution 2.16Å

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