Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligandTryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand

Structural highlights

6f9k is a 1 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.399Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TRPR_ECOLI This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

6f9k, resolution 1.40Å

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OCA