6cxm

Crystal structure of a dihydrofolate reductase from Mycobacterium smegmatis in complex with NADP and P218Crystal structure of a dihydrofolate reductase from Mycobacterium smegmatis in complex with NADP and P218

Structural highlights

6cxm is a 2 chain structure with sequence from Mycolicibacterium smegmatis MC2 155. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.65Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

I7FC10_MYCS2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194]

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OCA

6cxm

Crystal structure of a dihydrofolate reductase from Mycobacterium smegmatis in complex with NADP and P218Crystal structure of a dihydrofolate reductase from Mycobacterium smegmatis in complex with NADP and P218

Structural highlights

Function

See Also

Contents

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