6bo4

Open state structure of the full-length TRPV2 cation channel with a resolved pore turret domainOpen state structure of the full-length TRPV2 cation channel with a resolved pore turret domain

6bo4, resolution 4.00Å Show:Asymmetric Unit Biological Assembly Structural highlights 6bo4 is a 4 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 4Å Experimental data: Check Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TRPV2_RAT Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH (By similarity). See Also Ion channels 3D structures