5zkv

Solution structure of molten globule state of L94G mutant of horse cytochrome-cSolution structure of molten globule state of L94G mutant of horse cytochrome-c

Structural highlights 5zkv is a 1 chain structure with sequence from Equus caballus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR, 15 models Ligands: Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CYC_HORSE Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity). See Also Cytochrome C 3D structures

spinqualitylabelsall models 5zkv Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image