Crystal Structure of Oxidized Cypovirus Polyhedra R13A/E73C/Y83C MutantCrystal Structure of Oxidized Cypovirus Polyhedra R13A/E73C/Y83C Mutant

Structural highlights

5yrc is a 1 chain structure with sequence from Bombyx mori cypovirus 1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.67Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PYHD_CPVBM Major component of the virus occlusion bodies, which are large proteinaceous structures (polyhedra), that protect the virus from the outside environment for extended periods until they are ingested by insect larvae.

Publication Abstract from PubMed

Protein crystals are formed via ordered arrangements of proteins, which assemble to form supramolecular structures. Here, we show a method for the assembly of supramolecular protein cages within a crystalline environment. The cages are stabilized by covalent cross-linking allowing their release via dissolution of the crystal. The high stability of the desiccated protein crystals allows cages to be constructed.

Supramolecular protein cages constructed from a crystalline protein matrix.,Negishi H, Abe S, Yamashita K, Hirata K, Niwase K, Boudes M, Coulibaly F, Mori H, Ueno T Chem Commun (Camb). 2018 Feb 20;54(16):1988-1991. doi: 10.1039/c7cc08689j. PMID:29405208[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Negishi H, Abe S, Yamashita K, Hirata K, Niwase K, Boudes M, Coulibaly F, Mori H, Ueno T. Supramolecular protein cages constructed from a crystalline protein matrix. Chem Commun (Camb). 2018 Feb 20;54(16):1988-1991. doi: 10.1039/c7cc08689j. PMID:29405208 doi:http://dx.doi.org/10.1039/c7cc08689j

5yrc, resolution 1.67Å

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