5wx2
Crystal structure of porcine kidney D-amino acid oxidase mutant (I230A/R283G)Crystal structure of porcine kidney D-amino acid oxidase mutant (I230A/R283G)
Structural highlights
FunctionOXDA_PIG Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. See Also |
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