5u32
Crystal Structure of Fungal RNA KinaseCrystal Structure of Fungal RNA Kinase
Structural highlights
FunctionTRNL_CANAL One of the two proteins required for the splicing of precursor tRNA molecules containing introns. The ligation activity requires three enzymatic activities: phosphorylation of the 5' terminus of the 3' half-tRNA in the presence of ATP, opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester and ligation of the two tRNA halves in an ATP-dependent reaction. |
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