Crystal Structure of Human Glycine Receptor alpha-3 Mutant N38Q Bound to AM-3607Crystal Structure of Human Glycine Receptor alpha-3 Mutant N38Q Bound to AM-3607

Structural highlights

5tin is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.61Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GLRA3_HUMAN The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).

5tin, resolution 2.61Å

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OCA