Crystal structure of YEATS2 YEATS bound to H3K27cr peptideCrystal structure of YEATS2 YEATS bound to H3K27cr peptide

Structural highlights

5iql is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

YETS2_HUMAN Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.[1]

References

  1. Guelman S, Kozuka K, Mao Y, Pham V, Solloway MJ, Wang J, Wu J, Lill JR, Zha J. The double-histone-acetyltransferase complex ATAC is essential for mammalian development. Mol Cell Biol. 2009 Mar;29(5):1176-88. doi: 10.1128/MCB.01599-08. Epub 2008 Dec, 22. PMID:19103755 doi:10.1128/MCB.01599-08

5iql, resolution 2.10Å

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OCA