5h2c

Crystal structure of Saccharomyces cerevisiae Osh1 ANK - Nvj1Crystal structure of Saccharomyces cerevisiae Osh1 ANK - Nvj1

Structural highlights

5h2c is a 2 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3.508Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OSH1_YEAST Lipid-binding protein involved in maintenance of intracellular sterol distribution and homeostasis. Binds to phosphoinositides. May be involved in formation of PMN vesicles by altering the membrane lipid composition.^[1]

References

↑ Beh CT, Rine J. A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution. J Cell Sci. 2004 Jun 15;117(Pt 14):2983-96. Epub 2004 Jun 1. PMID:15173322 doi:http://dx.doi.org/10.1242/jcs.01157

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OCA

[1] Beh CT, Rine J. A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution. J Cell Sci. 2004 Jun 15;117(Pt 14):2983-96. Epub 2004 Jun 1. PMID:15173322 doi:http://dx.doi.org/10.1242/jcs.01157

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