Crystal structure of Marburg virus nucleoprotein core domain bound to VP35 regulation peptideCrystal structure of Marburg virus nucleoprotein core domain bound to VP35 regulation peptide

Structural highlights

5f5o is a 6 chain structure with sequence from Lake Victoria marburgvirus - Ozolin. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NCAP_MABVO Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).

See Also

5f5o, resolution 2.20Å

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OCA