5ejr

Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domainStructure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain

5ejr is a 1 chain structure with sequence from Dictyostelium discoideum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

MYOI_DICDI Myosins are actin-based motor molecules with ATPase activity. Involved in the early steps of phagocytosis and adhesion.^[1] ^[2] ^[3]

↑ Titus MA. A class VII unconventional myosin is required for phagocytosis. Curr Biol. 1999 Nov 18;9(22):1297-303. PMID:10574761
↑ Tuxworth RI, Weber I, Wessels D, Addicks GC, Soll DR, Gerisch G, Titus MA. A role for myosin VII in dynamic cell adhesion. Curr Biol. 2001 Mar 6;11(5):318-29. PMID:11267868
↑ Tuxworth RI, Stephens S, Ryan ZC, Titus MA. Identification of a myosin VII-talin complex. J Biol Chem. 2005 Jul 15;280(28):26557-64. Epub 2005 Apr 11. PMID:15826949 doi:http://dx.doi.org/M503699200