5ayc

Crystal structure of Ruminococcus albus 4-O-beta-D-mannosyl-D-glucose phosphorylase (RaMP1) in complexes with sulfate and 4-O-beta-D-mannosyl-D-glucoseCrystal structure of Ruminococcus albus 4-O-beta-D-mannosyl-D-glucose phosphorylase (RaMP1) in complexes with sulfate and 4-O-beta-D-mannosyl-D-glucose

Structural highlights

5ayc is a 1 chain structure with sequence from Ruminococcus albus 7 = DSM 20455. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.9Å
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MGP_RUMA7 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose. Involved in a mannan catabolic pathway which feeds into glycolysis.[HAMAP-Rule:MF_00928]^[1]

References

↑ Kawahara R, Saburi W, Odaka R, Taguchi H, Ito S, Mori H, Matsui H. Metabolic mechanism of mannan in a ruminal bacterium, Ruminococcus albus, involving two mannoside phosphorylases and cellobiose 2-epimerase: discovery of a new carbohydrate phosphorylase, beta-1,4-mannooligosaccharide phosphorylase. J Biol Chem. 2012 Dec 7;287(50):42389-99. doi: 10.1074/jbc.M112.390336. Epub 2012, Oct 23. PMID:23093406 doi:http://dx.doi.org/10.1074/jbc.M112.390336

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OCA

[1] Kawahara R, Saburi W, Odaka R, Taguchi H, Ito S, Mori H, Matsui H. Metabolic mechanism of mannan in a ruminal bacterium, Ruminococcus albus, involving two mannoside phosphorylases and cellobiose 2-epimerase: discovery of a new carbohydrate phosphorylase, beta-1,4-mannooligosaccharide phosphorylase. J Biol Chem. 2012 Dec 7;287(50):42389-99. doi: 10.1074/jbc.M112.390336. Epub 2012, Oct 23. PMID:23093406 doi:http://dx.doi.org/10.1074/jbc.M112.390336

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