Crystal structure of human sarcomeric mitochondrial creatine kinaseCrystal structure of human sarcomeric mitochondrial creatine kinase

Structural highlights

4z9m is a 8 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2gl6. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KCRS_HUMAN Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

See Also

4z9m, resolution 2.10Å

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