Crystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NADCrystal structure of 3-isopropylmalate dehydrogenase from Burkholderia thailandensis in complex with NAD

Structural highlights

4xxv is a 2 chain structure with sequence from Burkholderia thailandensis E264. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LEU3_BURTA Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]

See Also

4xxv, resolution 1.70Å

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