Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with XMPInosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with XMP

Structural highlights

4qq3 is a 1 chain structure with sequence from Vibrio cholerae O1 biovar El Tor str. N16961. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.72Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q9KTW3_VIBCH Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]

See Also

4qq3, resolution 1.72Å

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OCA