Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-aCalcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-a

Structural highlights

4qnh is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.02Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KCNN2_RAT Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.

See Also

4qnh, resolution 2.02Å

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OCA