Structure of Mus musculus Rheb G63A mutant bound to GTPStructure of Mus musculus Rheb G63A mutant bound to GTP

Structural highlights

4o2l is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RHEB_MOUSE Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity (By similarity).

See Also

4o2l, resolution 2.40Å

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