Crystal structure of human BS69 Bromo-Zinc finger-PWWPCrystal structure of human BS69 Bromo-Zinc finger-PWWP

Structural highlights

4ns5 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ZMY11_HUMAN Corepressor of transcription (Probable). May be involved in chromatin remodeling through association with several remodeling factors.[1] [2]

References

  1. Velasco G, Grkovic S, Ansieau S. New insights into BS69 functions. J Biol Chem. 2006 Jun 16;281(24):16546-50. Epub 2006 Mar 24. PMID:16565076 doi:http://dx.doi.org/10.1074/jbc.M600573200
  2. Masselink H, Bernards R. The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR. Oncogene. 2000 Mar 16;19(12):1538-46. PMID:10734313 doi:http://dx.doi.org/10.1038/sj.onc.1203421

4ns5, resolution 1.90Å

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