4mup

Crystal structure of Agrobacterium tumefaciens ATU3138 (EFI target 505157), apo structureCrystal structure of Agrobacterium tumefaciens ATU3138 (EFI target 505157), apo structure

Structural highlights

4mup is a 3 chain structure with sequence from Agrobacterium fabrum str. C58. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.6Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GLI_AGRFC Catalyzes the isomerization of D-galactaro-1,5-lactone to D-galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source.^[1]

References

↑ Bouvier JT, Groninger-Poe FP, Vetting M, Almo SC, Gerlt JA. Galactaro delta-lactone isomerase: lactone isomerization by a member of the amidohydrolase superfamily. Biochemistry. 2014 Feb 4;53(4):614-6. doi: 10.1021/bi5000492. Epub 2014 Jan 24. PMID:24450804 doi:http://dx.doi.org/10.1021/bi5000492

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OCA

[1] Bouvier JT, Groninger-Poe FP, Vetting M, Almo SC, Gerlt JA. Galactaro delta-lactone isomerase: lactone isomerization by a member of the amidohydrolase superfamily. Biochemistry. 2014 Feb 4;53(4):614-6. doi: 10.1021/bi5000492. Epub 2014 Jan 24. PMID:24450804 doi:http://dx.doi.org/10.1021/bi5000492

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