4l4s

Structural characterisation of the NADH binary complex of human lactate dehydrogenase M isozymeStructural characterisation of the NADH binary complex of human lactate dehydrogenase M isozyme

Structural highlights

4l4s is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.9Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

LDHA_HUMAN Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:612933. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.^[1]

Function

LDHA_HUMAN

References

↑ Maekawa M, Sudo K, Kanno T, Li SS. Molecular characterization of genetic mutation in human lactate dehydrogenase-A (M) deficiency. Biochem Biophys Res Commun. 1990 Apr 30;168(2):677-82. PMID:2334430

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OCA

[1] Maekawa M, Sudo K, Kanno T, Li SS. Molecular characterization of genetic mutation in human lactate dehydrogenase-A (M) deficiency. Biochem Biophys Res Commun. 1990 Apr 30;168(2):677-82. PMID:2334430

[1]

4l4s

Structural characterisation of the NADH binary complex of human lactate dehydrogenase M isozymeStructural characterisation of the NADH binary complex of human lactate dehydrogenase M isozyme

Structural highlights

Disease

Function

See Also

References

Contents

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