Proteopedia

4l15

Crystal structure of FIGL-1 AAA domainCrystal structure of FIGL-1 AAA domain

Structural highlights

4l15 is a 1 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.6Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FIGL1_CAEEL Has a role in spindle assembly which acts in the progression through mitosis during embryogenesis. Required for fertility.[1]

References

  1. ↑ Luke-Glaser S, Pintard L, Tyers M, Peter M. The AAA-ATPase FIGL-1 controls mitotic progression, and its levels are regulated by the CUL-3MEL-26 E3 ligase in the C. elegans germ line. J Cell Sci. 2007 Sep 15;120(Pt 18):3179-87. PMID:17878235 doi:10.1242/jcs.015883

4l15, resolution 2.60Å

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OCA
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